> ## Documentation Index
> Fetch the complete documentation index at: https://docs.purna.ai/llms.txt
> Use this file to discover all available pages before exploring further.

# Quickstart

> Get started with Purna in minutes. Sign in, start a research chat, and attach files.

Get up and running with Purna in a few minutes. You will sign in, choose a research mode, configure preferences, ask a question, and attach a file for analysis.

## Sign in to Purna

<Steps>
  <Step title="Open Purna">
    Navigate to **mip.purna.ai** in your web browser.
  </Step>

  <Step title="Sign in">
    Enter your Purna credentials. If you do not have an account, contact your organization administrator or use an [invitation link](/guides/team#joining-a-team) if one was shared with you.
  </Step>

  <Step title="View the home screen">
    After signing in, you will see the Purna home screen with suggested prompts and the chat input.

    ![Purna home screen](https://storage.googleapis.com/health_reports/web_images/docs/chat-home.png)
  </Step>
</Steps>

## Start a research chat

<Steps>
  <Step title="Choose a research mode">
    Use the **Research Mode** dropdown in the chat input. Choose **Biomedical Research** for literature, pathways, genes, proteins, diseases, and mechanisms. Choose **Omics Analysis** for RNA-seq, single-cell, multi-omics, and uploaded dataset analysis.
  </Step>

  <Step title="Choose a suggested prompt">
    The home screen offers starting points. Click any suggestion to begin, or type your own question.
  </Step>

  <Step title="Ask a focused question">
    Examples:

    * "What pathways connect EGFR resistance with MET amplification?"
    * "Summarize recent literature on TP53 gain-of-function variants."
    * "How should I QC this RNA-seq count matrix before differential expression?"
  </Step>

  <Step title="Review the response">
    Purna returns an evidence-backed answer. Tool indicators show which capabilities ran, and citation badges link back to source records.
  </Step>
</Steps>

<Tip>
  Specific questions produce better results. Include the organism, dataset type, experimental condition, disease area, or target output when you know it.
</Tip>

## Configure chat preferences

Click **Preferences** in the chat input to control how the current chat behaves.

<AccordionGroup>
  <Accordion title="Workflow modes">
    Turn on focused workflows such as **Deep Research**, **Consilium**, or **Paper Writing** when you need literature synthesis, structured debate, or manuscript drafting.
  </Accordion>

  <Accordion title="Capabilities">
    Enable or disable tool families such as web search, code execution, image generation, or background jobs. Some capabilities depend on your plan.
  </Accordion>

  <Accordion title="Skills and knowledge">
    Choose which knowledge sources and skill guidance Purna should use for the conversation.
  </Accordion>
</AccordionGroup>

<Note>
  Research mode is locked after the first message in a chat. Start a new chat when you want to switch between **Biomedical Research** and **Omics Analysis**.
</Note>

## Attach and reference files

<Steps>
  <Step title="Upload a file">
    Click the paperclip icon in the chat input to attach a file. You can upload CSV, TSV, JSON, FASTA, VCF, H5AD, BED, images, PDFs, text files, compressed archives, and other common research formats.
  </Step>

  <Step title="Reference existing files">
    Type `@` in the chat input to open the file picker. Select a file so Purna knows which dataset or document to inspect.
  </Step>

  <Step title="Ask for analysis">
    Ask Purna to inspect, summarize, transform, visualize, or process the file. For larger or multi-step work, ask it to start a background job.
  </Step>
</Steps>

## Organize work with projects

Projects keep related chats, files, jobs, and generated outputs together. New work starts in **Quick Research** unless you select another project.

<CardGroup cols={2}>
  <Card title="Projects" href="/guides/projects" icon="folder">
    Create workspaces for studies, campaigns, reviews, and team work.
  </Card>

  <Card title="Files" href="/guides/files" icon="folder-open">
    Browse uploaded files, generated outputs, and job artifacts.
  </Card>
</CardGroup>

## What's next?

<CardGroup cols={2}>
  <Card title="Chat" href="/guides/chat" icon="message-circle-2">
    Master research modes, preferences, citations, and artifacts.
  </Card>

  <Card title="Database search" href="/guides/genomic-search" icon="magnifying-glass">
    Query genomic, literature, pathway, protein, and drug databases.
  </Card>

  <Card title="Code execution" href="/code-execution/index" icon="terminal">
    Run Python and R analysis from chat.
  </Card>

  <Card title="Jobs" href="/guides/jobs" icon="gears">
    Launch autonomous pipelines for longer computational work.
  </Card>
</CardGroup>