What you can do with Purna
Agent Mode
Chat-first interface for genomics research. Ask natural language questions about genes, variants, diseases, and biological mechanisms — backed by real-time database lookups.
Case Mode
Organize your sequencing data into cases. Upload VCFs, track findings, manage phenotypes, and collaborate with your team — all in one workspace.
Variant analysis
Browse, filter, and prioritize genetic variants with card and table views. Apply gene panels, phenotype-driven filters, and population frequency thresholds.
ACMG classification
AI-enhanced ACMG/AMP variant classification with evidence pulled from ClinVar, PubMed, gnomAD, and functional data sources.
Database search
Access ClinVar, OMIM, PubMed, gnomAD, gene databases, and more. Toggle across five categories of research sources in every conversation.
Reports
Generate variant interpretation reports, findings summaries, ACMG evidence reports, and case overviews — ready for review or export.
Visualizations
Interactive charts generated from natural language. Pie, bar, line, and area charts — just describe what you want to see.
Code execution
Run Python and R code on a private compute server with pandas, matplotlib, Biopython, and 15+ scientific libraries pre-installed.
Explore the docs
Quickstart
Sign in and start using Purna in under 5 minutes.
AI chat
Master natural language queries, research sources, and artifacts.
Case management
Create and manage cases with VCF data.
Variant analysis
Browse and filter variants with the variant browser.
Variant detail
Deep-dive into individual variants across seven analysis tabs.
ACMG classification
AI-enhanced ACMG/AMP classification with evidence review.
Gene panels
Build and apply virtual gene panels for targeted analysis.
Settings
Personalize your workspace, manage usage, and configure your plan.
