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Get up and running with Purna in a few minutes. You will sign in, choose a research mode, configure preferences, ask a question, and attach a file for analysis.

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Sign in to Purna

1

Open Purna

Navigate to mip.purna.ai in your web browser.
2

Sign in

Enter your Purna credentials. If you do not have an account, contact your organization administrator or use an invitation link if one was shared with you.
3

View the home screen

After signing in, you will see the Purna home screen with suggested prompts and the chat input.Purna home screen

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Start a research chat

1

Choose a research mode

Use the Research Mode dropdown in the chat input. Choose Biomedical Research for literature, pathways, genes, proteins, diseases, and mechanisms. Choose Omics Analysis for RNA-seq, single-cell, multi-omics, and uploaded dataset analysis.
2

Choose a suggested prompt

The home screen offers starting points. Click any suggestion to begin, or type your own question.
3

Ask a focused question

Examples:
  • “What pathways connect EGFR resistance with MET amplification?”
  • “Summarize recent literature on TP53 gain-of-function variants.”
  • “How should I QC this RNA-seq count matrix before differential expression?”
4

Review the response

Purna returns an evidence-backed answer. Tool indicators show which capabilities ran, and citation badges link back to source records.
Specific questions produce better results. Include the organism, dataset type, experimental condition, disease area, or target output when you know it.

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Configure chat preferences

Click Preferences in the chat input to control how the current chat behaves.
Turn on focused workflows such as Deep Research, Consilium, or Paper Writing when you need literature synthesis, structured debate, or manuscript drafting.
Enable or disable tool families such as web search, code execution, image generation, or background jobs. Some capabilities depend on your plan.
Choose which knowledge sources and skill guidance Purna should use for the conversation.
Research mode is locked after the first message in a chat. Start a new chat when you want to switch between Biomedical Research and Omics Analysis.

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Attach and reference files

1

Upload a file

Click the paperclip icon in the chat input to attach a file. You can upload CSV, TSV, JSON, FASTA, VCF, H5AD, BED, images, PDFs, text files, compressed archives, and other common research formats.
2

Reference existing files

Type @ in the chat input to open the file picker. Select a file so Purna knows which dataset or document to inspect.
3

Ask for analysis

Ask Purna to inspect, summarize, transform, visualize, or process the file. For larger or multi-step work, ask it to start a background job.

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Organize work with projects

Projects keep related chats, files, jobs, and generated outputs together. New work starts in Quick Research unless you select another project.

Projects

Create workspaces for studies, campaigns, reviews, and team work.

Files

Browse uploaded files, generated outputs, and job artifacts.

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What’s next?

Chat

Master research modes, preferences, citations, and artifacts.

Database search

Query genomic, literature, pathway, protein, and drug databases.

Code execution

Run Python and R analysis from chat.

Jobs

Launch autonomous pipelines for longer computational work.